성명 : 호 원 경 (서울의대 생리학교실)
학력 및 경력
  • 1982-1986: Assistant in Department of Physiology, Seoul National University College of Medicine
  • 1986-1989: Instructor in Department of Physiology, College of Medicine Choongbuk National University
  • 1989-1991: Instructor in Department of Physiology, Seoul National University College of Medicine
  • 1991-1997: Assistant Professor in Department of Physiology, Seoul National University College of Medicine
  • 1997-2002: Associate Professor in Department of Physiology, Seoul National University College of Medicine
  • 2002-present: Professor in Department of Physiology, Seoul National University College of Medicine
  • 2006-2008: Associate Dean for Research Affairs in Seoul National University College of Medicine
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    연구관심분야
    Cellular excitability and Ion channel regulation
    주요연구실적
    1. Young-Eun Han, Ajin Lim, Sun-Hyun Park, Sunghoe Chang, Suk-Ho Lee, Won-Kyung Ho. Rac-mediated actin remodeling and myosin II are involved in KATP channel trafficking in pancreatic b-cells. Exp Mol Med. 2015 Oct 16; 47:e190
    2. Young-Eun Han, Shin-Young Ryu, Sun-Hyun Park, Kyu-Hee Lee, Suk-Ho Lee, Won-Kyung Ho. Ca2+ clearance by plasmalemmal NCLX, Li+-permeable Na+/Ca2+ exchanger, is required for the sustained exocytosis in rat insulinoma INS-1 cells. Pflugers Archiv. 2015
    3. Hye-Hyun Kim, Kyu-Hee Lee, Doyun Lee, Young-Eun Han, Suk-Ho Lee, Jong-Woo Sohn, and Won-Kyung Ho. Costimulation of AMPA and Metabotropic Glutamate Receptors Underlies Phospholipase C Activation by Glutamate in Hippocampus. Journal of Neuroscience. 35(16):6401-6412, 2015
    4. Sun-Hyun Park, Shin-Young Ryu, Woen-Jin Yu, Young Eun Han, Young-Sun Ji, Keunhee Oh, Jong-Woo Sohn, Ajin Lim, Jae-Pyo Jeon, Hyunsu Lee, Kyu-Hee Lee, Suk-Ho Lee, Per-Olof Beggren, Ju-Hong Jeon, and Won-Kyung Ho. Leptin promotes KATP channel trafficking by AMPK signaling in pancreatic -cells. PNAS 110 (31): 12673-8, 2013 Jul 30
    5. Sun-Hyun Park, Ju-Hong Jeon, and Won-Kyung Ho. AMPK regulates KATP channel trafficking via PTEN inhibition in leptin-treated pancreatic -cells. Biochem Biophys Res Commun 440(4): 539-44, 2013 Nov 1
    6. Sang Hun Lee, Kyung Ran Kim, Shin-Young Ryu, Sungmin Son, Hyun Seok Hong, Inhee Mook-Jung, Suk-Ho Lee, Won-Kyung Ho. Impaired short-term plasticity in Mossy fiber synapses caused by mitochondrial dysfunction of dentate granule cells is the earliest synaptic deficit in a mouse model of Alzheimer’s disease. J Neurosci 32(17):5953-5963, 2012 Apr 25
    7. Jae Sung Lee, Won-Kyung Ho, Suk-Ho Lee. Actin-dependent rapid recruitment of reluctant synaptic vesicles into a fast-releasing vesicle pools. PNAS 109(13):E765-774, 2012 Mar 27